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BOTOX has been used therapeutically for more than 17 years to treat a variety of medical conditions. It is approved in more than 75 countries and remains the most-studied botulinum toxin and one of the most widely researched medicines in the world. In 2002, the same formulation – under the label BOTOX Cosmetic – was approved by the US Food and Drug Administration (FDA) for treatment of moderate to severe frown lines between the brows in people ages 18 to 65.
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During treatment, very low doses of BOTOX Cosmetic are administered via a few tiny injections directly into the muscles responsible for frown lines between the brows. By blocking the release of a chemical that causes these muscles to contract, BOTOX Cosmetic enables them to relax. The effects are localized and, when administered by an experienced physician, do not affect your ability to smile, laugh, or otherwise show expression. BOTOX Cosmetic is the only product of its kind that has been approved for use in this area.
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The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness, and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious side effects.
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Both are cosmetic dermal fillers that replace lost volume and restore youthful contours to the skin to smooth away moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). Perlane gel particles are larger and designed for deeper injection than Restylane. Your doctor will decide which product is right for you.
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Restylane has been used in over 1.4 million treatments in the U.S. and is available in more than 70 countries. It is the most-studied cosmetic dermal filler in the world with dozens of publications in medical literature. Clinical studies showed no significant differences in the safety of Restylane and Perlane.
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Restylane and Perlane require no pretesting, but you should take a few precautions before being treated. Avoid using aspirin, non-steroidal anti-inflammatory medications, St. John’s Wort, or high doses of Vitamin E supplements prior to treatment, because these may increase bruising or bleeding at the injection site. Also, if you have previously suffered from facial cold sores, discuss this with your doctor, who may prescribe a medication to minimize recurrence.
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Restylane and Perlane are administered by injection to the treatment site. Before treatment talk to your doctor about pain management.
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